MLB
Final
Houston Astros
14-21
3
:
2
Cleveland Guardians
18-17
Tuesday, Apr 21, 2026 Season 2026
AI Win Prediction
45%
HOU
55%
CLE
Cleveland Guardians have a stronger record and home advantage, contributing to a higher win probability.
0:00
Subscription Required
Unlock Houston Astros vs Cleveland Guardians and every live game
Subscribe Now
HOU
CLE
14-21
Record
18-17
40%
Win %
51.4%
35
Games
35
Analysis
Watch Astros vs. Guardians: A High-Stakes MLB Showdown on April 21, 2026
As the MLB season heats up, all eyes will be on Progressive Field on April 21, 2026, as the Houston Astros visit the Cle...
Read →Astros vs. Guardians: Key Insights for the April 21, 2026 MLB Clash
On April 21, 2026, baseball fans will not want to miss the matchup between the Houston Astros and the Cleveland Guardian...
Read →Upcoming Games
Houston Astros