MLB
Final
Houston Astros
43-47
2
:
0
Cleveland Guardians
47-42
Wednesday, Apr 22, 2026 Season 2026
AI Win Prediction
45%
HOU
55%
CLE
Cleveland Guardians have a better record and home advantage, contributing to their higher win probability.
0:00
Subscription Required
Unlock Houston Astros vs Cleveland Guardians and every live game
Subscribe Now HOU
CLE
43-47
Record
47-42
47.8%
Win %
52.8%
90
Games
89
Analysis
Watch the Houston Astros Take on the Cleveland Guardians: A Clash of AL Contenders
As the Houston Astros gear up for their away game against the Cleveland Guardians on April 22, 2026, fans are eagerly an...
Read →Astros vs. Guardians: April 22 Showdown Set to Heat Up Baseball Fans
On April 22, 2026, the Houston Astros will face off against the Cleveland Guardians in a highly anticipated MLB showdown...
Read →Upcoming Games
Houston Astros
